Breast cancer stem cells: Multiple capacities in tumor metastasis
نویسندگان
چکیده
منابع مشابه
Cancer stem cells, tumor dormancy, and metastasis
Tumor cells can persist undetectably for an extended period of time in primary tumors and in disseminated cancer cells. Very little is known about why and how these tumors persist for extended periods of time and then evolve to malignancy. The discovery of cancer stem cells (CSCs) in human tumors challenges our current understanding of tumor recurrence, drug resistance, and metastasis, and open...
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Previous studies have shown that tumors can induce angiogenesis and lymphangiogenesis, which plays an important role in promoting hematogenous and lymphogenous spread. In recent years, the cancer stem cell (CSC) theory has emerged as an attractive hypothesis for tumor development and progression. The theory proposes that one small subset of cancer cells has the characteristics of stem cells. Th...
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Million of new cancer patients are diagnosed each year and over half of these patients die from this disease. As the second leading cause of cancer deaths, breast cancer in estimated to be diagnosed in over one million people worldwide and to cause more than 400,000 deaths each year. Chemotherapy is part of a successful treatment to many cases; however, the development of multidrug resistance (...
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ژورنال
عنوان ژورنال: Cancer Letters
سال: 2014
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2014.03.036